Internal Medicine, Family Medicine

Updates from the ACCP Guideline: Antithrombotic Therapy for VTE Disease

Paul R. Daniels, M.D.

What is the recommended anticoagulant for the long term treatment of DVT of the leg or PE in patients without cancer?
What is the recommended anticoagulant for the long term treatment of DVT of the leg or PE in patients with cancer?
Should I recommend aspirin to prevent recurrent VTE to patients with an unprovoked proximal DVT or PE who are stopping anticoagulation?
Should I recommend compression stockings to prevent post-thrombotic syndrome to patients with acute DVT of the leg?
Which patients with PE can I treat at home or dismiss early from the hospital?

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  • 0:00

    Introduction and Objectives

  • 3:56

    Abbreviations and Definitions

  • 4:42

    Question 1: Selection of AC for VTE patients WITHOUT cancer

  • 5:32

    ACCP Statement

  • 6:00

    NOAC verses VKA for acute VTE

  • 8:50

    Why not LMWH in patients WITHOUT cancer?

  • 9:26

    When to consider VKA over NOAC?

  • 11:47

    Question 2: Selection of AC for VTE patients WITH cancer

  • 12:24

    ACCP Statement

  • 14:39

    Why might LMWH be preferred for patients WITH cancer?

  • 15:37

    How to treat acute VTE in patients WITH cancer?

  • 16:51

    Question 3: Asprin and prevention of VTE

  • 16:52

    ACCP Statement

  • 18:07

    "Unprovoked" VTE

  • 19:38

    Clinical trials of asprin versus Placebo

  • 20:59

    Take away messages regarding asprin

  • 21:58

    Question 4: Role of compression stockings

  • 22:58

    ACCP Statement

  • 23:08

    Post-Thrombotic Syndrom

  • 25:41

    Role for compression stockings.

  • 27:22

    Question 5: PE treatment at home

  • 28:13

    ACCP Statement

  • 28:51

    Rationale for Outpatient Treadment of Acute PE

  • 32:16

    Mayo Clinic Guideline: Acute PE Treatment

  • 34:45

    Summary Points